Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells
- Creator: Neirijnck, Yasmine , Calvel, Pierre , Smith, Lee B. , Nef, Serge , Kilcoyne, Karen R. , Kühne, Françoise , Stévant, Isbelle , Griffeth, Richard J. , Pitetti, Jean-Lüc , Andric, Silvana A. , Hu, Meng-Chun , Pralong, François
- Resource Type: journal article
- Date: 2018
A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function
- Creator: Gannon, Anne-Louise , Darbey, Annalucia L. , Rebourcet, Diane , Chensee, Grace , Lawrence, Ben M. , O'Donnell, Liza , Kelso, Joanna , Reed, Natalie , Parameswaran, Shanmathi , Smith, Sarah , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
Exogenous gonadotrophin stimulation induces partial maturation of human sertoli cells in a testicular xenotransplantation model for fertility preservation
- Creator: Hutka, Marsida , Smith, Lee B. , Goossens, Ellen , Wallace, W. Hamish B. , Stukenborg, Jan-Bernd , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk
- Creator: Ashton, Katie , Proietto, Anthony , Otton, Geoffrey , Symonds, Ian , McEvoy, Mark , Attia, John , Gilbert, Michael , Hamann, Ute , Scott, Rodney J.
- Resource Type: journal article
- Date: 2010
Fertility preservation in childhood cancer: endocrine activity in prepubertal human testis xenografts exposed to a pubertal hormone environment
- Creator: Hutka, Marsida , Kadam, Prashant , Van Saen, Dorien , Homer, Natalie Z. M. , Onofre, Jaime , Wallace, W. Hamish B. , Smith, Lee B. , Stukenborg, Jan-Bernd , Goossens, Ellen , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies
- Creator: O'Hara, Laura , O'Shaughnessy, Peter J. , Freeman, Tom C. , Smith, Lee B.
- Resource Type: journal article
- Date: 2018
A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging
- Creator: Curley, Michael , Milne, Laura , Smith, Sarah , Jørgensen, Anne , Frederiksen, Hanne , Hadoke, Patrick , Potter, Paul , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells: LIFR Signalling in Leydig Cells
- Creator: Curley, Michael , Darbey, Annalucia , O'Donnell, Liza , Kilcoyne, Karen R. , Wilson, Kirsten , Mungall, Will , Rebourcet, Diane , Guo, Jingtao , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
Steroidogenic Enzyme Gene Expression and Testosterone Production are Developmentally Modulated by Bone Morphogenetic Protein Receptor-1B in Mouse Testis
- Creator: Ciller, Ilona , Palanisamy, Suresh , Ciller, Ursula , Al-Ali, Ibtisam , Coumans, Joëlle , Mcfarlane, James
- Resource Type: journal article
- Date: 2023